Normally this is a firewall issue. Our built-in email software does not use QSNADS. It is trying to make a direct connection to the destination mail server. For example, if you are trying to send an email to mailbox@mailserver.com, it first does a DNS lookup of mailserver.com. It looks at the mail exchange or MX records to find the public mail servers defined for this domain. It then attempts to connect directly to each of these mail servers on port 25.
You can test this connectivity outside of our software using the following procedure:
1) use a web site like www.mxtoolbox.com to lookup the public MX records for the destination mail server
2) run the TELNET RMTSYS(MAIL1.MAILSERVER.COM) PORT(25) command on your iSeries for each of the mail server domains found in the lookup
3) if the TELNET command just hangs, your firewall is likely blocking the outgoing TCP/IP traffic from your iSeries IP address directly to the destination mail server IP address on port 25
4) if this is allowed through your firewall, our mail software should just automatically start working